Clinical Science

Oxystorm® : Nitrate surge for an INSTANT Nitric Oxide Boost!

Universal energy currency of the living world is mainly synthesized by the mitochondria of the cell , the power house, that occupy 20% of the cell volume which utilizes oxygen . The energy produced is exported to all parts of the body to provide energy for the cellular work. Economy of energy conversion is very crucial during vigorous exercises or else it may lead to oxygen debt. In a recent study (Subramanian et al.,2016)it was observed that Oxystorm can deliver high nitrate and enhance nitric oxide levels in the body (Graph 1). Our clinical studies have shown that Oxystorm® enhances the nitric oxide by converting nitrate to nitrite. Nitric oxide generated from Oxystorm® enhances VO2 and maximize the energy produced and thus reduces extreme fatigue and physical weakness during strenuous exercise or physical activity.

Nitric oxide has been identified as an important endothelium derived relaxing factor, which is released from the endothelium and results in vascular smooth muscle relaxation (Palmer et al., 1987). The authors have also reported that the increased level of nitric oxide is due to the high level of nitrite in saliva (Graph 2)

Pharmacokinetic study of amaranth extract in healthy humans: A randomized trial

Research
Graph1- Plasma nitrate (NO3ˉ) level after administration of amaranth extract and placebo (highly significant difference (p<0.001) between amaranth and placebo group at all the time points except 0 h and 24 h)
Research
Graph2- Saliva nitrite (NO2ˉ) level after administration of amaranth extract and placebo (highly significant difference (p<0.001) between amaranth and placebo group at all the time points except 0 h and 24 h)



Differential vascular reactivity responses acutely following ingestion of a nitrate rich red spinach extract

Research
Research

Fig1: Plasma concentrations of total nitrate and nitrite (NOx; a) and nitrite only (b) at baseline and 30- and 65- to 75-min following ingestion of a red spinach extract (RSE; filled circles) and placebo (PBO; open circles). Data are presented as mean absolute values in μM concentrations ± SD. When a significant time × condition interaction was observed, post hoc tests were performed using Student’s paired t tests. *,**Significantly different from baseline within condition (P ≤ 0.05 and 0.01, respectively). †,††Significantly different between condition at the same time point (P ≤ 0.05 and 0.01, respectively)

A randomised double blind placebo controlled, crossover study conducted in The Edward Via College of Osteopathic Medicine , USA with a single oral dose of 1000 mg ; published in Eur J Appl Physiol, DOI 10.1007/s00421-016-3478-8.